New Delhi-Scientists from IIT Guwahati have synthesised mats made of silk-proteins and bioactive glass fibres that they believe can assist the growth of bone cells and repair worn-out joints in arthritis patients.<\/p>\n
The disease most commonly affects joints in the knees, hips, hands, feet, and spine and is marked by the breakdown of joint cartilage and underlying bones.<\/p>\n
Left untreated, it can cause severe pain, swelling, and eventually limited range of movement.<\/p>\n
“Current clinical treatment methods are limited by lack of viable tissue substitutes to aid the repair process,” Biman B Mandal from Indian Institute of Technology Guwahati (IITG) told PTI.<\/p>\n
To develop a suitable tissue substitute, scientists, including those from the University College London in the UK, looked into the natural bone-cartilage interface and tried to mimic it synthetically in lab conditions.<\/p>\n
Knee osteoarthritis is the most common bone and joint disease in India. However, Mandal pointed out that the available clinical grafts were expensive.<\/p>\n
“We used silk, a natural protein to fabricate electrospun mats to mimic the cartilage portion and bioactive glass to develop a composite material, similar to the natural tissue,” said Mandal.<\/p>\n
For the mat, scientists used a kind of silk easily available in North-east India.<\/p>\n
“Muga (Assam) silk is endowed with properties that enhance the healing process,” he said.<\/p>\n","protected":false},"excerpt":{"rendered":"
New Delhi-Scientists from IIT Guwahati have synthesised mats made of silk-proteins and bioactive glass fibres that they believe can assist the growth of bone cells and repair worn-out joints in arthritis patients. The disease most commonly affects joints in the knees, hips, hands, feet, and spine and is marked by the breakdown of joint cartilage […]<\/p>\n","protected":false},"author":1,"featured_media":1400,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[239],"tags":[],"class_list":["post-1399","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"_links":{"self":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts\/1399","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/comments?post=1399"}],"version-history":[{"count":1,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts\/1399\/revisions"}],"predecessor-version":[{"id":1401,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts\/1399\/revisions\/1401"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/media\/1400"}],"wp:attachment":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/media?parent=1399"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/categories?post=1399"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/tags?post=1399"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}