The new drug selectively shrinks excess fat by increasing fat cell metabolism, according to the researchers. The researchers discovered a molecule that blocks metabolic brake from operating in obese white fat cells. By blocking this metabolic brake, they were able to increase the metabolism of white fat cells.<\/p>\n
\u201cBlocking the action of the fat cell brake provides an innovative \u2018fat\u2019 specific mechanism to increase cell metabolism and reduce the size of white fat deposits, thereby treating a root cause of obesity and related metabolic diseases,\u201d said the lead author of the study, Harshini Neelakantan from University of Texas Medical Branch .<\/p>\n
According to a recent study, published in the journal Biochemical Pharmacology, the drug significantly reduces body weight and blood cholesterol levels without lowering food intake in obese mice. In the study, mice were fed a high-fat diet until they became obese and then received either the drug or a placebo.<\/p>\n
Following 10 days of drug treatment, researchers found that the obese mice receiving the actual drug lost more than seven per cent of their total body weight and their white fat tissue mass and cell size decreased by 30 per cent compared with the placebo group.<\/p>\n
In addition, blood cholesterol in drug-treated mice were lowered to normal levels, similar to those of non-obese mice. On the contrary, placebo-treated mice continued to accumulate white fat and gain weight throughout the study.<\/p>\n
Interestingly, mice in both the drug-treated and placebo groups consumed the same amount of food during the course of the study period, showing that the fat loss was not due to appetite suppression. \u201cThese initial results are encouraging and support further development of this technology as a new and more effective approach to combating metabolic diseases,\u201d Neelakantan noted.<\/p>\n","protected":false},"excerpt":{"rendered":"
The new drug selectively shrinks excess fat by increasing fat cell metabolism, according to the researchers. The researchers discovered a molecule that blocks metabolic brake from operating in obese white fat cells. By blocking this metabolic brake, they were able to increase the metabolism of white fat cells. \u201cBlocking the action of the fat cell […]<\/p>\n","protected":false},"author":1,"featured_media":17408,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[239],"tags":[],"class_list":["post-17407","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"_links":{"self":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts\/17407","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/comments?post=17407"}],"version-history":[{"count":1,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts\/17407\/revisions"}],"predecessor-version":[{"id":17409,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts\/17407\/revisions\/17409"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/media\/17408"}],"wp:attachment":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/media?parent=17407"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/categories?post=17407"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/tags?post=17407"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}