{"id":41880,"date":"2018-09-12T11:08:20","date_gmt":"2018-09-12T11:08:20","guid":{"rendered":"http:\/\/blastingskyhawk.com\/?p=41880"},"modified":"2018-09-12T11:08:20","modified_gmt":"2018-09-12T11:08:20","slug":"how-binge-drinking-affects-male-female-brains","status":"publish","type":"post","link":"https:\/\/blastingskyhawk.com\/english\/how-binge-drinking-affects-male-female-brains\/","title":{"rendered":"How binge drinking affects male, female brains?"},"content":{"rendered":"<p><strong>While binge drinking affects the health of both males and females, the effect of gene expression in an area of the brain linked to addiction was found to be different, finds a new study.<\/strong><\/p>\n<p>Repeated binge drinking was found to significantly alter molecular pathways in the nucleus accumbens a region of the brain linked to addiction.<\/p>\n<p>But, in females, the genes linked to hormone signalling and immune function are altered, whereas in males genes related to nerve signalling are affected.<\/p>\n<p>The study has significant implications for the treatment of alcohol use disorder as they emphasise the importance of tailoring effective therapies towards male and female patients, said researchers led by Deborah Finn, Professor at Oregon Health and Science University.<\/p>\n<p>Repeated binge drinking can be a risk factor for the development of alcohol dependence.<\/p>\n<p>For the study, published in the journal Frontiers in Genetics, the team analysed gene expression in nucleus accumbens.<\/p>\n<p>\u201cWe examined the effect of repeated binge drinking on the expression of 384 genes previously identified as important in addiction and mood disorders,\u201d Finn said.<\/p>\n<p>Of a total of 106 genes regulated by binge drinking, only 14 were regulated in both males and females, representing common targets to binge drinking. Interestingly, only 4 of these 14 genes were regulated in the same direction and the top 30 genes regulated by binge drinking in each sex differed markedly.<\/p>\n<!-- AddThis Advanced Settings generic via filter on the_content --><!-- AddThis Share Buttons generic via filter on the_content -->","protected":false},"excerpt":{"rendered":"<p>While binge drinking affects the health of both males and females, the effect of gene expression in an area of the brain linked to addiction was found to be different, finds a new study. Repeated binge drinking was found to significantly alter molecular pathways in the nucleus accumbens a region of the brain linked to [&hellip;]<!-- AddThis Advanced Settings generic via filter on get_the_excerpt --><!-- AddThis Share Buttons generic via filter on get_the_excerpt --><\/p>\n","protected":false},"author":1,"featured_media":41881,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[239],"tags":[],"class_list":["post-41880","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"_links":{"self":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts\/41880","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/comments?post=41880"}],"version-history":[{"count":1,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts\/41880\/revisions"}],"predecessor-version":[{"id":41882,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts\/41880\/revisions\/41882"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/media\/41881"}],"wp:attachment":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/media?parent=41880"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/categories?post=41880"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/tags?post=41880"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}