{"id":45322,"date":"2018-10-25T11:28:39","date_gmt":"2018-10-25T11:28:39","guid":{"rendered":"http:\/\/blastingskyhawk.com\/?p=45322"},"modified":"2018-10-25T11:28:39","modified_gmt":"2018-10-25T11:28:39","slug":"exercise-can-help-boost-memory-through-bone-hormone","status":"publish","type":"post","link":"https:\/\/blastingskyhawk.com\/english\/exercise-can-help-boost-memory-through-bone-hormone\/","title":{"rendered":"Exercise can help boost memory through bone hormone"},"content":{"rendered":"<p><strong>Researchers have identified a naturally occurring bone hormone that can potentially reverse memory loss in the ageing brain through exercise.<\/strong><\/p>\n<p>The study on the hormone osteocalcin lends new insight into how lifestyle changes that affect the body, such as exercise, could positively affect the brain.<br \/>\n&#8220;Nearly everyone will experience age-related memory loss in their lifetime, so it is incredibly important to understand its causes and identify ways to mitigate it,&#8221; said Eric R. Kandel, Professor at the Columbia University.<\/p>\n<p>&#8220;With today&#8217;s study, we are not only building a detailed understanding of how age-related memory loss originates in the brain, we&#8217;ve shown how osteocalcin interacts with key proteins in the brain to boost memory.&#8221; For many years, memory loss was treated as a singular disorder. But scientists have now begun to realise that Alzheimer&#8217;s disease, begins in a part of the brain called the entorhinal cortex, which lies at the foot of the hippocampus.<\/p>\n<p>Kandel&#8217;s team identified a deficiency in a protein called RbAp48 protein, a significant contributor to age-related memory loss but not Alzheimer&#8217;s. The protein levels decline with age, both in mice and in people.<\/p>\n<p>In a series of experiments, reported in the journal Cell Reports, the team found that RbAp48 controls the expression levels of two other proteins regulated from osteocalcin.<\/p>\n<p>If RbAp48 function is inhibited, osteocalcin infusions have no effect on the animals&#8217; memory. Osteocalcin needs RbAp48 to kick start the process.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers have identified a naturally occurring bone hormone that can potentially reverse memory loss in the ageing brain through exercise. The study on [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":45323,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[239],"tags":[],"class_list":["post-45322","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"_links":{"self":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts\/45322","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/comments?post=45322"}],"version-history":[{"count":1,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts\/45322\/revisions"}],"predecessor-version":[{"id":45324,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts\/45322\/revisions\/45324"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/media\/45323"}],"wp:attachment":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/media?parent=45322"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/categories?post=45322"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/tags?post=45322"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}