{"id":8139,"date":"2017-10-21T12:37:01","date_gmt":"2017-10-21T12:37:01","guid":{"rendered":"http:\/\/punjabnews24.com\/?p=8139"},"modified":"2017-10-21T12:37:01","modified_gmt":"2017-10-21T12:37:01","slug":"cafestol-a-bioactive-substance-found-in-coffee-could-help-delay-onset-of-type-2-diabetes","status":"publish","type":"post","link":"https:\/\/blastingskyhawk.com\/english\/cafestol-a-bioactive-substance-found-in-coffee-could-help-delay-onset-of-type-2-diabetes\/","title":{"rendered":"\u2018Cafestol\u2019, a bioactive substance found in coffee, could help delay onset of Type-2 diabetes"},"content":{"rendered":"<p>The medicine that can delay your diabetes is right on your coffee table.<\/p>\n<p>\u2018Cafestol\u2019, a bioactive substance found in coffee, could help delay the onset of Type-2 diabetes, improve cell function and insulin sensitivity in laboratory mice, according to a study carried out by a team of<\/p>\n<p>scientists in Denmark.<\/p>\n<p>This is yet another research finding that has driven coffee from its universal role as a breakfast beverage into the list of items that can be recommended for a healthy diet and lifestyle. For instance, recently<\/p>\n<p>researchers at the University of Southern California in the US &#8211; in a study of more than 1,80,000 participants &#8211; found that drinking coffee could lead to a longer life.<\/p>\n<p>Researchers have also earlier identified substances in coffee that could help reduce the risk of developing diabetes but \u2018cafestol\u2019 is one substance that has so far been untested.<\/p>\n<p>In their study, the researchers wanted to see if \u2018cafestol\u2019 would help prevent or delay the onset of Type-2 diabetes in mice. The findings have been reported in the American Chemical Society Journal of Natural<\/p>\n<p>Products.<\/p>\n<p>According to the authors, \u201cthe finding could spur the development of new drugs to treat or even prevent the disease\u201d. For their study, the scientists chose a model of mice &#8211; called KKAy mice &#8212; that are prone<\/p>\n<p>to develop diabetes. Forty-seven male mice were randomly divided into two groups &#8211; treatment and control groups.<\/p>\n<p>While all the mice consumed a normal diet, the mice in the treatment group were fed daily with \u2018cafestol\u2019 for 10 weeks. The animals in the control group were not given \u2018cafestol\u2019. At the end, blood samples for<\/p>\n<p>fasting glucose, glucagon and insulin as well as liver, muscle and fat tissues for gene expression analysis were collected.<\/p>\n<p>The researchers isolated islets of Langerhans &#8211; which produce insulin &#8211; and measured their insulin secretory capacity. \u201cAfter 10 weeks of intervention, fasting plasma glucose was 28-30% lower in \u2018cafestol\u2019<\/p>\n<p>group compared with the control group,\u201d the researchers report.<\/p>\n<p>\u201cFasting glucagon was 20% lower and insulin sensitivity improved by 42% in the high-cafestol group. Cafestol increased insulin secretion from isolated islets by 75-87% compared to the control group.\u201d The<\/p>\n<p>researchers conclude their results show that cafestol possesses anti-diabetic properties in mice.<\/p>\n<!-- AddThis Advanced Settings generic via filter on the_content --><!-- AddThis Share Buttons generic via filter on the_content -->","protected":false},"excerpt":{"rendered":"<p>The medicine that can delay your diabetes is right on your coffee table. \u2018Cafestol\u2019, a bioactive substance found in coffee, could help delay the onset of Type-2 diabetes, improve cell function and insulin sensitivity in laboratory mice, according to a study carried out by a team of scientists in Denmark. This is yet another research [&hellip;]<!-- AddThis Advanced Settings generic via filter on get_the_excerpt --><!-- AddThis Share Buttons generic via filter on get_the_excerpt --><\/p>\n","protected":false},"author":1,"featured_media":8140,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[239],"tags":[],"class_list":["post-8139","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"_links":{"self":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts\/8139","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/comments?post=8139"}],"version-history":[{"count":1,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts\/8139\/revisions"}],"predecessor-version":[{"id":8141,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/posts\/8139\/revisions\/8141"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/media\/8140"}],"wp:attachment":[{"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/media?parent=8139"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/categories?post=8139"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blastingskyhawk.com\/english\/wp-json\/wp\/v2\/tags?post=8139"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}