World No. 1 and defending champion Rafael Nadal came back from a set and break down to defeat big-hitting Karen Khachanov 5-7 7-5 7-6 (9/7) 7-6 (7/3) and reach the US Open fourth round. The top seeded Spaniard triumphed after an epic 4 hour, 23 minute struggle at Arthur Ashe Stadium in a match where the 22-year-old Khachanov had served for a two sets to love lead in the 10th game of the second set and had a set point in the fourth-set tiebreaker.

Basilashvili reached the last-16 of a Slam for the first time by seeing off Argentina’s Guido Pella 6-3 6-4 1-6 7-6 (7/4).
South Africa’s Kevin Anderson outlasted Canadian teenager Denis Shapovalov 4-6 6-3 6-4 4-6 6-4 as the roof on the new Louis Armstrong Stadium was closed for the first time.

The fifth seed next faces ninth-seeded Austrian Dominic Thiem, who made the last-16 for the fourth time in five years with a 3-6 6-3 7-6 (7/5) 6-4 victory over American Taylor Fritz. John Isner fired 34 aces, 85 winners and saved the three break points he faced in beating Serbia’s Dusan Lajovic 7-6 (10/8) 6-7 (6/8) 6-3 7-5.

He will face Milos Raonic who put out 2016 champion Stan Wawrinka 7-6 (8/6) 6-4 6-3. Croatian Borna Coric made the last-16 of a Slam for the first time with a 6-3 7-5 6-2 victory over Russia’s Daniil Medvedev.